产品名称 | cox-2 Antibody |
反应种属 | Human, Mouse, Rat |
应用 | WB, IHC |
推荐稀释比 | WB 1:500-1000, IHC 1:100-300 |
蛋白分子量 | 69kDa |
宿主 | Rabbit |
克隆类型 | Polyclonal Antibody |
储存 | -20℃ |
背景资料 | Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. |