产品名称 | NFκB p65 Antibody |
反应种属 | Human, Mouse, Rat |
应用 | WB, IHC |
推荐稀释比 | WB 1:1000-2000, IHC 1:300-500 |
蛋白分子量 | 59/60kDa |
宿主 | Rabbit |
克隆类型 | Polyclonal Antibody |
储存 | -20℃ |
背景资料 | NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. |